If you experience any of the following please consult your doctor:

• Severe abdominal pain or persistent painful swelling of the abdomen

• Vomiting for more than 24 hours

• Diarrhoea not responding to your usual medication

• Bleeding from the back passage

• Weight loss

• Persistent tiredness and fatigue

• A change in bowel habit, (e.g. diarrhoea to constipation or constipation to diarrhoea)

• Side effects or any unusual reactions from your medications as highlighted in the appropriate information sheets